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Endocrine Abstracts

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ea0026p192 | Pituitary | ECE2011

Adipocytes as a source of increased circulating levels of NAMPT/visfatin in active acromegaly

Olarescu C , Ueland T , Lekva T , Dahl T B , Aukrust P , Halvorsen B , Bollerslev J

Background: Nicotinamide phosphoribosyltransferase (NAMPT)/PBEF/visfatin is a widely expressed cytokine with various effects on glucose and lipid metabolism, cell survival, and inflammation. Despite a favorable body composition profile, acromegalic patients present insulin resistance, increased cardiovascular risk, and higher incidence of secondary tumors.Aim: Based on its relation to glucose and lipid metabolism and inflammation we hypothesized that NAM...
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ea0026p251 | Pituitary | ECE2011

Lost to follow-up in acromegaly, results of ACROSPECT observational study

Delemer B D , Reines C R , Brue T B , Rudelli C C Cortet , Raingeard I R , Reznik Y R , Parot X P , Chabre O C

Lost to follow-up (LTFU) is a frequent problem in chronic diseases not evaluated yet in acromegaly despite the long-term need of medical treatment and complications survey in this disease.Objectives: Evaluation of the prevalence of LTFU patients in a multi-center cohort, characteristics of defaulters and description of their evolution after they have been searched and found.Méthods: Observational multicentric (25 centers study...
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Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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